Effectiveness of fluoride varnish four times a year in preventing caries in the primary dentition: A 2 year randomized controlled trial.

Community Dent Health. 2019 Aug 20. doi: 10.1922/CDH_4453Begzati05. [Epub ahead of print]

Abstract

OBJECTIVES:

To test the effectiveness of fluoride varnish in preventing caries in early childhood in children at high risk of caries.

BASIC RESEARCH DESIGN:

Randomized controlled trial.

PARTICIPANTS:

504 participants, with mean age of 21 months at baseline randomly allocated into a test and a control group. 427 children remained in the study after two years.

INTERVENTION:

Fluoride varnish applied four times a year, every three months. The intervention lasted for two years.

MAIN OUTCOME MEASURES:

Dental status was recorded based on the International Caries Detection and Assessment System (ICADS).

RESULTS:

Mean dmfs was similar in the control and test groups at baseline (1.0 and 1.2 respectively) but was significantly different (10.1 and 5.2, p ⟨ 0.001, ANOVA) at endpoint. The proportion caries free in the two groups was 40% and 69.4% after two years.

CONCLUSIONS:

The application of fluoride varnish four times a year prevented the incidence and reduced the severity of caries in pre-school children.

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